| Ealson Pro-Active Security | Johannesburg | Provider of SASSETA Accredited Security officers f | |
| Ear & Allergy Clinic Singapore | | Medical Clinic | |
| EarCandy Dubbing | Johannesburg | Dubbing Studio & Audio Post | |
| Earlyworx 282 | Randburg | PVC Card solutions, Card printers | |
| Earnnick | | Payment processing for both online and offline bus | |
| Earth Africa | Durban | African Beadwork and rural crafts | |
| Earth Probiotic Recycling Solutions | Randburg | On-site organic waste management composting. | |
| Earthwool | Johannesburg | Knuaf Earthwool Insulation With Ecose Technology | |
| Easemyedu | | Easemyedu | |
| Easicompli | Durbanville | Company Registrations, CIPC Compliance | |
| eAskme Business | | Marketing | |
| East Jaguar International | | saxilby, East london | |
| East London Coffee | East London | Coffee roasting & equipment sales & rent. | |
| East Rand Paint & Waterproofing | springs | Rubberising, waterproofing, paint, decor | |
| East Rand Plumbing Services | Benoni | PLUMBING REPAIRS & DRAIN CLEANING MANTENANCE | |
| East Side Signs | Pretoria | Signage | |
| East SSD Chemical Slab | | money | |
| Eastern Cape Women Magazine | Mthatha | Eastern Cape Women Magazine | |
| Eastwave Radio | | Community Radio | |
| Easy Beesy Auto Hives | Ceres | Beekeeping supplies | |
| Easy Collect & Drop | Midrand | Delivery service | |
| Easy Earn | | merketing | |
| Easy Grasse | Cape Town | Artificial Grass | |
| Easy Loot | Salt Lake City | Investment Service | |
| Easy Move Lift | | Marketing | |
| Easy Shade Ports | Bellville | At Easy Shade, we specialise in Shadeports for res | |
| Easy way Shopping | Johannesburg | Online shopping and delivery services | |
| EasyAs! Point of Sale Business Software | Cape Town | Point of Sale | |
| EasyDebit Payment Solutions | Alberton | Payment Solutions | |
| Easydoesit | Johannesburg | IT store | |
| Eatfresh | Durban | Staff Restaurants and Canteen Solutions | |
| Eaton Consulting Services | Cape Town | BBBEE & HR Consulting Services | |
| Eazy Ads | Johannesburg | OOH (Out Of Home) Outdoor Advertising. | |
| Eazy Events and Tours | Pretoria | Tour Operator | |
| Eben Business Solutions | | Project manager & Industrial Engineering services | |
| Ebenezer Unlimited Creations | Johannesburg | Cleaning Sevices | |
| EBNewsDaily | Pretoria | News Publishing | |
| Ebonds Soshanguve | Pretoria / Tshwane | eBonds is a residential bond originating company | |
| Ebony+Ivory Ad Agency | Somerset West | Full service advertising agency | |
| EC Training Network | Johannesburg | Management, Staff & personal training and developm | |
| Echo Logistics | New Germany | Echo Logistics | |
| Echo Productions & Radio Advertising | Pretoria | Radio & TV advertising and productions | |
| Echo Setup | | Echo support | |
| Echo Square PR | Johannesburg | Public Relations | |
| EchoVine Communications | Durbanville | Content Marketing and Communication Strategists | |
| Eclipse Communications | Cape Town | Public Relations | |
| Eclipse Communications Johannesburg | Johannesburg | Public Relations, Marketing & Digital | |
| Eco Card | KEMPTON PARK | Plastic Card Manufacturer | |
| Eco D Wash South Africa | Cape Town | Manufacuring,marketing,franchising | |
| Eco Foam | Johannesburg | Spray Insulation | |
| Eco Fumigation | Centurion | Pest control | |
| Eco Furniture Design | Cape Town | furniture store | |
| Eco Mobile Valet | Cape Town | Car wash | |
| Eco Pest Control | Johannesburg | Pest controlling | |
| Eco Pest Control Service | Johannesburg | Pest Control | |
| Eco Slayer Cape Town | Cape Town | Eco friendly Pest, Insect, Bird and Rodent Control | |
| Eco Topia | Bellville | Organic and Eco-Friendly Products | |
| Eco Valet | Parow | Mobile Car Wash and Valet | |
| Eco-Logic Publishing - The Enviropaedia | Cape Town | Enviropaedia, Eco-Logic Awards | |
| Eco-Pest Control | Johannesburg | Pest Control | |
| Eco-Smart Pest Control | Gauteng | Pest Control | |
| Ecoaches and Tours | Nelspruit | Airport transfers, tours , car hire | |
| EcoDux | Pretoria | Company Secretarial Services and Taxation, | |
| Ecology SA (Pty) Ltd | Nigel | all spects regarding Health and Safety | |
| eCommerce Websites | Bloemfontein | eCommerce Websites | |
| Econo Driver Training | Port Elizabeth | Training provider accredited with TETA. | |
| Economic Development Solutions | Johannesburg | BBBEE Strategy Consulting/SED/ED Plans | |
| EconoServices | Johannesburg | Consulting on compliance, B-BBEE, EE & SD | |
| EcoPack | Cape Town | Sustainable, compostable & biodegradable packaging | |
| Ecotel-inc | Johannesburg | direct marketing | |
| ECS Associates | Johannesburg | Construction and Engineering Contract Management | |
| Ed Unique | Strand | Peer Ed, HIV AIDS, Life Skills, Stress Management | |
| Edblo Trusted Sleep | Johannesburg | Manufacturing base sets | |
| Eddie Goldberg Productions (EG Productions) | Cape Town | Video's for social media and radio ads and jingles | |
| Eden Financial Group South Africa | Johannesburg | Loans/Cash/Money | |
| Eden Lawns | Sedgefield | Grass sales | |
| Edge Bathrooms | | bathroom specialists | |
| Edge Multimedia | Cape Town | Digital Marketing in video, animation & design | |
| Edge Professional | Edenvale | Education and training | |
| Edge Training | Durban | Skills Development and training solutions | |
| Ediify - Digital Marketing Courses In Vashi Navi Mumbai | Thane | EDIIFY - Digital Marketing Courses in Vashi | |
| Edistera | | software making | |
| Editage Academy | Pretoria | Tutoring, Research, Data Analysis, Editing Service | |
| Edonia Logistics Services | Johannesburg | Import/Export Logistics Solutions | |
| Edot Digital | Johannesburg | Web Design, SEO, Google Ads Partner | |
| Edteach Reader | | online tuttion | |
| Edu Consultantss | | Edu consultants | |
| EduAdmin | Sandton | Education administration Software | |
