Cardiology News South Africa

Landmark study identifies heart rate as a new risk factor for heart attacks

When your heart beats faster it's not always a good thing.

ew clinical trial data have confirmed what many heart specialists have suspected for years. If your heart consistently beats too fast, you are at increased risk of suffering a heart attack, stroke or heart failure.

The findings of the landmark BEAUTIfUL trial were announced at a major cardiology conference in Europe recently and have confirmed years of accumulating evidence that if you have coronary heart disease and your heart beats too fast, your risk of suffering a major cardiac event is higher.

It's common knowledge that if you want to keep your heart healthy, you need to eat sensibly and exercise regularly. Smoking, being overweight and having high blood pressure and/or cholesterol levels all contribute to your risk of developing heart diseases. Losing weight, quitting smoking and managing high blood pressure/cholesterol are therefore important to maintain optimal heart health - but still may not be enough if your heart beats too fast all the time.

Johannesburg cardiologist, Dr Colin Schamroth, says, “We have data to show that as heart rate increases so does the likelihood of heart failure and sudden death. This relationship is linear and independent of other cardiac risk factors, such as high blood pressure and cholesterol. The association was present in 37 of 39 studies and shows a consistency similar to that of smoking when it comes to predicting the risk of heart disease.”

A key finding of the BEAUTIfUL study was that the increase in risk was noted when the resting heart rate - i.e. the number of times the heart beats per minute when an individual is not actively exercising - rose above 70 beats per minute. Until now, doctors had generally defined a dangerously high heart rate as being greater than 90 beats per minute.

“The take-home message is that in patients with coronary artery disease, a heart rate of more than 70 beats per minute is indeed a risk factor for future events,” says Dr Schamroth. “The BEAUTIfUL results suggest that we may need to redefine a ‘stable cardiac patient' and also reassess what ‘normal' is when it comes to heart rate.”

The good news, however, is that an overly high heart rate can be treated and controlled. A new drug, the first of its kind, will soon be available in South Africa. It lowers heart rate in a way that does not impact on other aspects of the heart's functioning. It even has a built-in safety mechanism in that it has more dramatic effects when the heart rate is especially high, but a much lower impact when the heart rate is only slightly elevated.

The BEAUTIfUL study showed that using this new medication to lower heart rate was associated with significant reductions in the rate of admission to hospital with a heart attack, as well as the need for certain invasive heart procedures. It has a very good safety profile and is almost completely free of side effects.

In addition, this new drug is good for relieving the chest pain associated with angina, but without the side effects of other drugs used for angina. It does not cause fatigue, sexual problems, ankle swelling, depression or cold extremities.

For more information, speak to your doctor or pharmacist, or visit www.beautiful-study.com



Editorial contact

Kim Rudman
011 431-2359

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